Research Article
A Chinese Herbal Medicine, Jia-Wei-Xiao-Yao-San, Prevents Dimethylnitrosamine-Induced Hepatic Fibrosis in Rats
Table 1
Effects of JWXYS and silymarin on the body weights of rats with DMN-induced chronic liver injury.
| Group | Time after DMN treatment (day) | | | 0 | 14 | 28 | 42 |
| A | Normal control | 148.0 ± 12.2 | 214.0 ± 13.3 | 282.0 ± 33.9 | 348.8 ± 35.5 | B | DMN (10 mg/kg) | 143.7 ± 23.3 | 190.7 ± 19.3 | 225.7 ± 10.5 | 265.7 ± 11.0* | C | DMN (10 mg/kg) + silymarin (200 mg/kg) | 145.0 ± 20.0 | 193.2 ± 16.8 | 273.2 ± 22.0 | 325.2 ± 28.7 | D | DMN (10 mg/kg) + JWXYS (100 mg/kg) | 144.7 ± 17.3 | 190.7 ± 16.9 | 272.7 ± 16.3 | 324.8 ± 16.2 | E | DMN (10 mg/kg) + JWXYS (300 mg/kg) |
145.0 ± 16.9 | 190.2 ± 16.9 | 273.0 ± 16.4 | 325.6 ± 17.2 | F | DMN (10 mg/kg) + JWXYS (1000 mg/kg) | 145.0 ± 20.0 | 195.2 ± 16.9 | 277.0 ± 17.2 | 331.8 ± 18.2# |
|
|
Each value is presented as the mean ± SE ().
*
, significantly different from Group A.
#, significantly different from Group B.
|