Research Article

A Chinese Herbal Medicine, Jia-Wei-Xiao-Yao-San, Prevents Dimethylnitrosamine-Induced Hepatic Fibrosis in Rats

Table 1

Effects of JWXYS and silymarin on the body weights of rats with DMN-induced chronic liver injury.

GroupTime after DMN treatment (day)
0142842

ANormal control148.0 ± 12.2214.0 ± 13.3282.0 ± 33.9348.8 ± 35.5
BDMN (10 mg/kg)143.7 ± 23.3190.7 ± 19.3225.7 ± 10.5265.7 ± 11.0*
CDMN (10 mg/kg) + silymarin (200 mg/kg)145.0 ± 20.0193.2 ± 16.8273.2 ± 22.0325.2 ± 28.7
DDMN (10 mg/kg) + JWXYS (100 mg/kg)144.7 ± 17.3190.7 ± 16.9272.7 ± 16.3324.8 ± 16.2
EDMN (10 mg/kg) + JWXYS (300 mg/kg) 145.0 ± 16.9190.2 ± 16.9273.0 ± 16.4325.6 ± 17.2
FDMN (10 mg/kg) + JWXYS (1000 mg/kg)145.0 ± 20.0195.2 ± 16.9277.0 ± 17.2331.8 ± 18.2#

Each value is presented as the mean ± SE ( ).
* , significantly different from Group A.
# , significantly different from Group B.