A Chinese Herbal Medicine, Jia-Wei-Xiao-Yao-San, Prevents Dimethylnitrosamine-Induced Hepatic Fibrosis in Rats

Table 2

Effects of JWXYS on the SGOT, SGPT, and albumin levels in rats with DMN-induced chronic liver injury.

Group		SGOT	SGPT	Albumin
		(IU/L)	(IU/L)	(g/dL)
A	Normal control	105.3 ± 13.9	24.2 ± 3.3	4.45 ± 0.02
B	DMN (10 mg/kg)	320.1 ± 42.3^##	80.3 ± 11.8^##	3.24 ± 0.04^#
C	DMN (10 mg/kg) + silymarin (200 mg/kg)	200.4 ± 17.6**	66.7 ± 11.1**	3.87 ± 0.14**
D	DMN (10 mg/kg) + JWXYS (100 mg/kg)	211.3 ± 15.6**	70.1 ± 7.6*	3.76 ± 0.15
E	DMN (10 mg/kg) + JWXYS (300 mg/kg)	193.6 ± 11.8**	63.3 ± 7.3**	3.86 ± 0.16**
F	DMN (10 mg/kg) + JWXYS (1000 mg/kg)	168.3 ± 9.9**	47.3 ± 6.8**	3.96 ± 0.18**

Values are presented as the mean ± SE (𝑛=10).
^#,##𝑃<0.05 and 0.01, significantly different from Group A.
^*,**𝑃<0.05 and 0.01, significantly different from Group B.
One-way analysis of variance coupled with Dunnett’s test.
P values < 0.05 indicated significance.