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The Scientific World Journal
Volume 2014, Article ID 232535, 7 pages
http://dx.doi.org/10.1155/2014/232535
Research Article

Effects of Nonsurgical Periodontal Therapy on Clinical Response, Microbiological Profile, and Glycemic Control in Malaysian Subjects with Type 1 Diabetes

1Department of Restorative Dentistry, Faculty of Dentistry, University of Malaya, 50603 Kuala Lumpur, Malaysia
2Oral Cancer Research and Coordinating Center, Department of Oral Biology and Biomedical Science, Faculty of Dentistry, University of Malaya, 50603 Kuala Lumpur, Malaysia
3Department of Endocrinology, University of Malaya Medical Center, 50603 Kuala Lumpur, Malaysia
4Oral Cancer Research and Coordinating Center, Department of Oro-Maxillofacial and Medical Science, Faculty of Dentistry, University of Malaya, 50603 Kuala Lumpur, Malaysia

Received 29 March 2014; Revised 1 July 2014; Accepted 10 July 2014; Published 23 July 2014

Academic Editor: Reginaldo Bruno Gonçalves

Copyright © 2014 Samira Mukhtar Buzinin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The association between diabetes mellitus and chronic periodontal disease has long been established. Most of the researches linking these two very common chronic diseases were based on type 2 diabetes mellitus and chronic periodontal disease. However, this study was conducted to investigate the association between type 1 diabetes and chronic periodontal disease in Malaysian subjects. Forty-one Malaysian subjects, of which 20 subjects were type 1 diabetics and with chronic periodontal disease (test group) and 21 subjects with only chronic periodontal disease (control group), were included in the study. Periodontal parameters and plaque samples for microbiological evaluation were done at baseline, 2 and 3 months after nonsurgical periodontal therapy. Blood samples were taken from only the test group and evaluated for HbA1c at baseline and 3 months after periodontal therapy. There were no statistically significant difference in periodontal parameters between groups ( ) and no significant improvement in the level of HbA1c in the test group. Microbiological studies indicated that there were significant reductions in the levels of the tested pathogens in both groups. The results of our study were similar to the findings of several other studies that had been done previously.