Diverse Effects of Lead Nitrate on the Proliferation, Differentiation, and Gene Expression of Stem Cells Isolated from a Dental Origin
Figure 4
((a) and (b)) Gene expression analysis of bone marrow stem cells (BM-MSCs), deciduous stem cells (SCDs), periodontal ligament stem cells (PDLs), and permanent stem cells (DPSCs) for control and after treatment of Pb2+ at 160 μmol. BM-MSCs, SCDs, DPSCs, and PDLs were tested against gene repair enzyme (ERCC3, XRCC14, RAD 51), stemness and self-renewal (Nanog, Rex 1, Oct 4), endoderm lineage (HNF-4α, SOX 17), and ectoderm lineage (SOX 1, KRT-15, NURR1). The lower a cycle threshold value is, the more copies are present in the specific sample. Values are presented after being normalized to 18s mRNA levels. The average of 3 replicates is displayed.
