A Mild Synthesis of New Aryl Vinyl Ethers and Diethyl 1-[(Alkyl)(cyano)methyl]vinylphosphonates via the Substitution of a 2,3-Difunctional Allyl Bromide

Table 2

Synthesis of diethyl 1-[(alkyl)(cyano)methyl]vinylphosphonates 4a–d.

Product	RMgX (equiv.)	Yield (%)^a
4a	EtMgBr (1.5)	74
4b	^𝑖PrMgBr (1.5)	92
4c	^𝑖BuMgBr (2)	88
4d	Me3SiCH2MgCl (1.5)	78

aIsolated yields obtained after purification by chromatography.