Synthesis and Antioxidant Evaluation of Enantiomerically Pure Bis-(1,2,3-triazolylmethyl)amino Esters from Modified α-Amino Acids

Table 3

Yield and antioxidant activity of bis-(1,2,3-triazolylmethyl)amino esters 6.

Product	R^1	R^2	Yield %	Antioxidant activity; IC50 (µg mL^−1)^a
6a	–CH3	–CH3	65	317.68 ± 74.16
6b	–CH2Indol	–CH3	76	774.26 ± 112.64
6c	–H	–CH2CH3	50	75.57 ± 1.74
6d	–CH2OH	–CH2CH3	55	—
Vitamin C			—	8.48 ± 1.07
Gallic acid			—	6.33 ± 0.66

^aValues represent mean ± standard deviation, n = 3.