A Quantitative Method for the Characterization of Lytic Metastases of the Bone from Radiographic Images

Table 2

AUC values of the ROC curve for the three parameters (mean (MGL), standard deviation (SDGL), and coefficient of variation (CVGL) of gray level) considered and their corresponding significance. Null hypothesis tested (AUC = 0.5) corresponds to a null diagnostic value to differentiate between multiple myeloma and osteolytic metastases groups.

AUC values
Groups	MGL	SDGL	CVGL
MM1—OL1	0.420; (𝑃 = 0.60)	0.467; (𝑃 = 0.83)	0.600; (𝑃 = 0.52)
MM2—OL2	0.758; (𝑃 = 0.048)	0.883; (𝑃 = 0.003)	0.483; (𝑃 = 0.89)

Note. Multiple myeloma: MM1 (nonflat bone) and MM2 (flat bone); osteolytic metastases: OL1 (nonflat bone) and OL2 (flat bone). AUC: the area under the ROC curve.