The Effect of Maternal Stress Activation on the Offspring during Lactation in Light of Vasopressin

Figure 3

Effect of 10 min maternal separation (single housed without bedding in a 2 L glass jar) on serum hormone levels in 7-day-old control and AVP-deficient Brattleboro rat pups. 𝑁=21–28 This short separation was able to increase both the ACTH (a) and corticosterone (b) levels in the offspring. However, AVP-deficient animals had smaller ACTH reaction to stress, while their corticosterone elevations were even higher than in normal animals. ^∗𝑃<0.05, ^∗∗𝑃<0.01 versus AVP+; ^##𝑃<0.01 versus nonstressed control.

(a)

(b)