The Effect of Maternal Stress Activation on the Offspring during Lactation in Light of Vasopressin

Figure 5

Serum stress hormone levels after 10 min openfield exposure (description of the procedure: [24]). Control and separated (single 24 h maternal separation on postnatal day 9: [22]) normal and AVP-deficient Brattleboro rats were compared at the age of 40 day. 𝑁=9–15 Previous 24 h maternal separation led to reduced ACTH (a) and corticosterone (b) rises in juveniles. AVP-deficiency diminished the stressor-induced changes, without affecting the corticosterone levels. ^∗𝑃<0.05, ^∗∗𝑃<0.01 versus AVP+; ^#𝑃<0.05, ^##𝑃<0.01 versus nonseparated control.

(a)

(b)