The Effect of Maternal Stress Activation on the Offspring during Lactation in Light of Vasopressin

Figure 6

Effect of maternal genotype on the offspring’s stress reactivity in adulthood. 𝑁=11–16 In adults, 60 min restraint [25] significantly elevated both the ACTH (a) and corticosterone (b) levels. The ACTH elevation was smaller in the AVP-deficient offspring of AVP-deficient mothers compared both to normal progenies and to AVP-deficient offspring of normal mothers. The genotypes had no effect on corticosterone elevations. ^∗∗𝑃<0.01 versus AVP+ offspring; ⁺⁺𝑃<0.01 versus AVP− offspring of AVP+ mother; ^##𝑃<0.01 versus nonstressed control.

(a)

(b)