Renoprotective Effect of Egyptian Cape Gooseberry Fruit (Physalis peruviana L.) against Acute Renal Injury in Rats

Table 3

Effect of Physalis peruviana  L. extract on serum creatinine, urea, and BUN in normal and cisplatin induced ARI rats.

	Creatinine mg/dL	Urea mg/dL	BUN mg/dL
Normal control	0.65±0.04^a	23.33±2.88^a	10.90±1.35^a
PPE100	0.68±0.02^a	24.67±2.31^a	11.53±1.08^a
PPE150	0.66±0.05^a	22.27±2.52^a	10.59±1.18^a
Cisplatin	3.56±0.81^d	125.67±5.03^d	58.72±1.77^d
PPE100 + cisplatin	1.97±0.04^c	83.33±3.51^c	38.94±1.64^c
PPE150 + cisplatin	1.01±0.34^b	62.24±2.08^b	29.28±0.97^b

Values are expressed as mean ± SD. Mean values within a column not sharing the same superscript letters were significantly different. 𝑃≤0.05; BUN: blood urea nitrogen. PPE100 and PPE150: 100 and 150 mg Physalis peruviana  L. extract/Kg BW, respectively.