Cytotoxic Activities of Flavonoids from Centaurea scoparia

Table 2

Cytotoxicity (IC₅₀ in μM)^a of compounds 1–10 isolated C. scoparia.

IC50 (μM)
Cell lines; Compound	HeLa	MCF-7	HepG2
1	3.21±0.21	4.23±0.11	3.91±0.54
2	0.079±0.03	0.32±0.08	0.64±0.12
3	11.98±1.79	12.21±1.81	13.39±1.3
4	13.54±2.1	12.96±1.57	14.24±1.21
5	0.11±0.02	0.14±0.04	0.25±0.05
6	8.14±1.28	6.52±1.40	4.4±0.50
7	9.31±0.91	11.33±1.12	12.41±0.94
8	1.12±0.74	5.93±1.12	4.2±1.30
9	1.71±0.18	7.75±1.31	5.7±0.85
10	3.54±1.89	9.98±1.89	7.14±1.97
Deguelin	6.21±0.82	5.17±0.94	0.65±0.11

aThe data shown are means ± SD obtained from three independent experiments.