Review Article
Endocrinopathies after Allogeneic and Autologous Transplantation of Hematopoietic Stem Cells
Table 1
Risk factors for gonadal damage.
| | Risk factor degree |
| Patient relating factor | | Pubertal stage | Postpuberal >prepuberal | Age of HSCT in women | >30 years | Sex | F > M | Underlying disease | ALL, lymphomas | Treatment relating factor | | Type of radiotherapy | TBI, pelvic, inverted Y, fractionated doses | Chemotherapy | Alkylating agents > other chemotherapy | Type of transplant | Previous TBI Allo-HSCT >auto-HSCT | HSCT complications | Presence of GVHD |
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ALL: acute lymphoblastic leukemia; allo: allogeneic; auto: autologous; GVHD: graft-versus-host disease; HSCT: hematopoietic stem cell transplant; F: female; M: male; TBI: “total body” irradiation. Symbol (>) means more than.
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