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The Scientific World Journal
Volume 2014, Article ID 312704, 7 pages
http://dx.doi.org/10.1155/2014/312704
Research Article

Association between a Variant in MicroRNA-646 and the Susceptibility to Hepatocellular Carcinoma in a Large-Scale Population

1Department of Digestive Diseases, Huashan Hospital, Fudan University, 12 Middle Wulumuqi Road, Shanghai 200040, China
2Department of Immunology of Shanghai Medical School and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China
3Ministry of Education Key Laboratory of Contemporary Anthropology and State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200433, China
4Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China

Received 23 March 2014; Revised 6 July 2014; Accepted 21 July 2014; Published 7 August 2014

Academic Editor: Manuela Ferracin

Copyright © 2014 Rui Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [6 citations]

The following is the list of published articles that have cited the current article.

  • Ping Zhang, Jianguo Wang, Ting Lu, Xiaofeng Wang, Yabiao Zheng, Shicheng Guo, Yajun Yang, Mengyun Wang, Vijay Kumar Kolluri, Lixin Qiu, Fangyuan Shen, Lixia Fan, Jin Li, Yanong Wang, Qingyi Wei, Li Jin, Jiucun Wang, and Minghua Wang, “miR-449b rs10061133 and miR-4293 rs12220909 polymorphisms are associated with decreased esophageal squamous cell carcinoma in a Chinese population,” Tumor Biology, vol. 36, no. 11, pp. 8789–8795, 2015. View at Publisher · View at Google Scholar
  • Yunhu Pan, Yitan Chen, Fangyu Cao, Debin Ma, Zhiyu Ji, Zhibin Chen, Yunye Ning, and Chong Bai, “miR-646 is a key negative regulator of EGFR pathway in lung cancer,” Experimental Lung Research, vol. 42, no. 6, pp. 286–295, 2016. View at Publisher · View at Google Scholar
  • Yanyun Ma, Deqing Zeng, Rui Wang, Jingyi Hu, Wenshuai Li, Jie Liu, Jun Zhang, Dongqin Yang, Heping Hu, and Jiucun Wang, “Association between microRNA single nucleotide polymorphisms and the risk of hepatocellular carcinoma,” Revista Medica de Chile, vol. 144, no. 4, pp. 508–515, 2016. View at Publisher · View at Google Scholar
  • Joel Henrique Ellwanger, Francis Maria Báo Zambra, Rafael Lima Guimarães, and José Artur Bogo Chies, “MicroRNA-Related Polymorphisms in Infectious Diseases—Tiny Changes With a Huge Impact on Viral Infections and Potential Clinical Applications,” Frontiers in Immunology, vol. 9, 2018. View at Publisher · View at Google Scholar
  • Yun-xiao Zhou, Chuan Wang, Li-wei Mao, Yan-li Wang, Li-qun Xia, Wei Zhao, Jie Shen, and Jun Chen, “Long noncoding RNA HOTAIR mediates the estrogen-induced metastasis of endometrial cancer cells via the miR-646/NPM1 axis,” American Journal of Physiology-Cell Physiology, vol. 314, no. 6, pp. C690–C701, 2018. View at Publisher · View at Google Scholar
  • Yi Niu, Zeng Ye, Chun-You Wang, Shuai Zhu, Xiang Li, Chi He, Zhu Zeng, Jian-Xin Zhong, Gang Zhao, Heng-Yu Chen, Yan Jin, Shi-Chang Deng, Shi-Jiang Deng, Yang Liu, and Ming-Liang Liu, “MiRNA-646-mediated reciprocal repression between HIF-1α and MIIP contributes to tumorigenesis of pancreatic cancer,” Oncogene, vol. 37, no. 13, pp. 1743–1758, 2018. View at Publisher · View at Google Scholar