An Approach to Differential Diagnosis of Antiphospholipid Antibody Syndrome and Related Conditions

Table 1

Main differential diagnosis of APS with usual clinical manifestations.

(i) Microangiopathic syndromes (TTP/HUS, HELLP)*
(ii) Heparin induced thrombocytopenia (HIT)
(iii) Disseminated intravascular coagulation (DIC)
(iv) Systemic lupus erythematosus
(v) Behçet’s syndrome

TTP: thrombotic thrombocytopenic purpura; HUS: hemolytic uremic syndrome; HELLP: hemolysis, elevated liver enzymes, and low platelets.