Protective Effects of Aqueous Extract of Solanum nigrum Linn. Leaves in Rat Models of Oral Mucositis

Table 4

Change in hematological parameter on 7th day of study period in methotrexate induced oral mucositis.

Groups	WBC (×10^3 cells/mm^3)	RBC (×10^6 cells/mm^3)	PLT (×10^3 cells/mm^3)
Normal control	15.02 ± 1.48	7.96 ± 0.16	583.2 ± 16.43
Mucositis control	3.0 ± 1.20^a	7.86 ± 0.19	169.33 ± 30.02^a
L-Glutamine	8.51 ± 0.79	6.86 ± 0.26	259.66 ± 17.79^a,b
AESN (100 mg/kg)	8.95 ± 2.55	6.36 ± 0.61	179.66 ± 16.83^a
AESN (200 mg/kg)	9.31 ± 1.0	6.94 ± 0.36	233.33 ± 6.65^a

All values are expressed as mean ± SEM of 6 samples. ^a < 0.05 versus normal control, ^b < 0.05 versus mucositis control.