Protective Effects of Aqueous Extract of Solanum nigrum Linn. Leaves in Rat Models of Oral Mucositis

Table 5

Change in hematological parameter on 12th day of study period in methotrexate induced oral mucositis.

Groups	WBC (×10^3 cells/mm^3)	RBC (×10^6 cells/mm^3)	PLT (×10^3 cells/mm^3)
Normal control	16.1 ± 0.73	8.01 ± 0.22	583.2 ± 16.43
Mucositis control	3.0 ± 1.20^a	7.86 ± 0.19	169.33 ± 30.02^a
L-Glutamine	14.8 ± 1.35^b	5.34 ± 0.28	513.21 ± 99.70
AESN (100 mg/kg)	11.12 ± 1.83^b	5.62 ± 0.47	281.25 ± 31.83^a
AESN (200 mg/kg)	13.6 ± 3.36^b	5.34 ± 0.71	384.33 ± 67.17

All values are expressed as mean ± SEM of 6 samples. ^a < 0.05 versus normal control, ^b < 0.05 versus mucositis control.