Enoxaparin Prevents Steroid-Related Avascular Necrosis of the Femoral Head
Enoxaparin treatment decreases glucocorticoid-induced osteonecrosis. The application of enoxaparin with methylprednisolone reduces significantly the amount of empty osteocyte lacunae per mm2 in the femoral head of rabbits due to methylprednisolone treatment to control levels. The graph represents the mean score with SEM of empty lacunae. Statistical analysis was performed with one-way ANOVA followed by Bonferroni’s multiple comparison test (control versus GC, control versus GC + Clexane, and GC versus GC + Clexane). ().