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The Scientific World Journal
Volume 2014, Article ID 357403, 9 pages
http://dx.doi.org/10.1155/2014/357403
Research Article

Anticonvulsant Potential of Certain New (2E)-2-[1-Aryl-3-(1H-imidazol-1-yl)propylidene]-N-(aryl/H)hydrazinecarboxamides

1Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia
2Pharmaceutical and Drug Industries Research Division, Medicinal and Pharmaceutical Chemistry Department (Medicinal Chemistry Group), National Research Centre, Dokki, Giza 12622, Egypt
3Pharmaceutical and Drug Industries Research Division, Medicinal and Pharmaceutical Chemistry Department (Pharmacology Group), National Research Centre, Dokki, Giza 12622, Egypt

Received 23 August 2013; Accepted 30 September 2013; Published 12 January 2014

Academic Editors: K. Abouzid and E. Acquas

Copyright © 2014 Mohamed I. Attia et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [7 citations]

The following is the list of published articles that have cited the current article.

  • Reem I. Al-Wabli, Mohamed I. Attia, Hazem A. Ghabbour, Nahed N. E. El-Sayed, and Hoong-Kun Fun, “Crystal structure of (2E)-2-[1-(4-bromophenyl)-3-(1H-imidazol-1-yl) propylidene]-N-(2,4-dichlorophenyl) hydrazinecarboxamide, C19H16BrCl2N5O,” Zeitschrift Fur Kristallographie-New Crystal Structures, vol. 230, no. 3, pp. 217–218, 2015. View at Publisher · View at Google Scholar
  • Mohamed I. Attia, Hazem A. Ghabbour, and Hoong-Kun Fun, “Crystal structure of (2E)-2-[3-(1H-imidazol-1-yl)-1-phenylpropylidene]-hydrazinecarboxamide monohydrate, C13H17N5O2,” Zeitschrift Fur Kristallographie-New Crystal Structures, vol. 230, no. 3, pp. 249–250, 2015. View at Publisher · View at Google Scholar
  • Jayanta Kumar Patra, Gitishree Das, and Kwang-Hyun Baek, “Chemical composition and antioxidant and antibacterial activities of an essential oil extracted from an edible seaweed, Laminaria japonica L,” Molecules, vol. 20, no. 7, pp. 12093–12113, 2015. View at Publisher · View at Google Scholar
  • Munusamy Govindarajan, Ali Abdelhameed, Abdulaziz Al-Saadi, and Mohamed Attia, “Experimental and Theoretical Studies of the Vibrational and Electronic Properties of (2E)-2-[3-(1H-imidazol-1-yl)-1-phenyl-propylidene]-N-phenylhydrazinecarboxamide: An Anticonvulsant Agent,” Applied Sciences, vol. 5, no. 4, pp. 955–972, 2015. View at Publisher · View at Google Scholar
  • Nadia G. Haress, Munusamy Govindarajan, Reem I. AL-Wabli, Maha S. Almutairi, Monirah A. Al-Alshaikh, Abdulaziz A. Al-Saadi, and Mohamed I. Attia, “Spectroscopic (FT-IR, FT-Raman, UV, 1H and 13C NMR) profiling and theoretical calculations of (2E)-2-[3-(1H-imidazol-1-yl)-1-phenylpropylidene]hydrazinecarboxamide: an anticonvulsant agent,” Journal of Molecular Structure, 2016. View at Publisher · View at Google Scholar
  • Reem I. Al-Wabli, Devarasu Manimaran, Liji John, Isaac Hubert Joe, Nadia G. Haress, and Mohamed I. Attia, “ Spectroscopic Investigations, DFT Calculations, and Molecular Docking Studies of the Anticonvulsant (2 E )-2-[3-(1 H -Imidazol-1-yl)-1-phenylpropylidene]- N -(4-methylphenyl)hydrazinecarboxamide ,” Journal of Spectroscopy, vol. 2016, pp. 1–10, 2016. View at Publisher · View at Google Scholar
  • Walaa Hamada Abd-Allah, Mona Elsayed Aboutabl, Mohamed Nabil Aboul-Enein, and Aida Abdel Sattar El-Azzouny, “Synthesis, molecular modeling studies and anticonvulsant activity of certain (1-(benzyl (aryl) amino) cyclohexyl) methyl esters,” Bioorganic Chemistry, vol. 71, pp. 135–145, 2017. View at Publisher · View at Google Scholar