Research Article
RRHGE: A Novel Approach to Classify the Estrogen Receptor Based Breast Cancer Subtypes
Algorithm 1
Pseudocode for the RRHGE algorithm.
| Let defines the set of subnetwork based-gene signature, denotes the hub-gene with their | | interactors in subnetwork and defines the th training set. | | FOR | | { | | Initialize: | | Step 1. Evaluate for all subnetworks and identify the top based subnetwork. | | { | | FOR each subnetwork from the list of available subnetworks in | | { | | COMPUTE | | } | | ENDFOR | | IF | | THEN | | AND remove from the list of available subnetworks in | | } | | Step 2. Evaluate for all subnetworks and identify the significant hub-genes with their interactors. | | { | | COMPUTE | | FOR each subnetwork from the list of available subnetworks in | | { | | COMPUTE | | { | | IF | | THEN | | } | | } | | ENDFOR | | } | | } | | RETURN | | END |
|
