Dietary Hyaluronic Acid Migrates into the Skin of Rats

Table 3

The distribution of radioactivity in selected organs and tissues as (photostimulated luminescence-background)/area after single oral administration of ¹⁴C hyaluronic acid to rats at a dose of 25 mg/kg.

No.	Tssue	Distribution of radio activity (PSL/mm^2)
		8 hr	24 hr	96 hr
1	Adrenal gland	3.74	4.94	2.11
2	Blood	2.12	1.68	0.84
3	Bone marrow	4.88	5.00	1.31
4	Brain	1.20	0.88	0.54
5	Brown fat	4.66	3.68	2.16
6	Epididymis	1.76	1.03	0.69
7	Eyeball	0.57	0.38	0.26
8	Fat	0.83	0.83	1.19
9	Gastric contents	0.59	0.10	0.04
10	Harderian gland	12.27	18.75	2.72
11	Heart	3.09	1.27	0.88
12	Intestinal contents	710.02	86.68	0.28
13	Intestine	6.60	8.16	2.09
14	Kidney	5.79	3.93	1.51
15	Liver	9.22	4.48	1.42
16	Lung	4.10	2.93	1.21
17	Mandibular gland	7.49	2.65	1.31
18	Pancreas	17.45	2.10	1.02
19	Pituitary gland	3.67	3.58	1.60
20	Prostate gland	2.99	3.13	1.13
21	Seminal vesicle	4.03	2.43	2.34
22	Skeletal muscle	1.68	1.04	0.83
23	Skin	2.36	3.81	1.98
24	Spleen	6.07	4.43	1.84
25	Stomach	5.34	3.75	1.30
26	Testes	0.88	0.86	0.57
27	Thymus	3.16	2.99	1.45
28	Thyroid gland	5.45	4.54	1.52
29	Urine in bladder	6.20	0.34	0.06