Research Article

Modeling the Differences in Biochemical Capabilities of Pseudomonas Species by Flux Balance Analysis: How Good Are Genome-Scale Metabolic Networks at Predicting the Differences?

Figure 1

(a) In silico modeling of Pseudomonas species growth on benzoate under different oxygen regimes. In all three cases, biomass production increases as the oxygen uptake flux increases. The same pattern exists in all of the models. However, experimental data suggested different trends of response to the available environmental oxygen. (b) Benzoate uptake flux under different oxygen regimes. Similar to the growth rate, flux of the uptake reaction increases as the available environmental oxygen concentration augments in contrast to the experimental data.
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(a)
416289.fig.001b
(b)