In Vitro Sustained Release Study of Gallic Acid Coated with Magnetite-PEG and Magnetite-PVA for Drug Delivery System

Table 2

Correlation coefficient, rate constant, and half-time obtained by fitting the data of the release of GA from FPEGG and FPVAG nanocomposites into phosphate buffered solutions at pH 4.8 and 7.4.

Aqueous solution	Saturated release %	𝑅^2			Rate constant (𝑘)^a (mg/min)	𝑡1/2^a (min)
		Pseudo-first order	Pseudo-second order	Parabolic diffusion
pH 7.4*	60.9	0.7893	0.9992	0.8651	6.41×10^−5	254
pH 4.8*	89.4	0.9168	0.9950	0.9567	1.92×10^−5	568
pH 7.4**	80.9	0.5984	0.9953	0.9816	3.49×10^−5	323
pH 4.8**	86.4	0.9887	0.9989	0.8220	8.19×10^−5	141

∗Estimation was done for the release of GA from FPEGG nanocomposite. **Estimation was done for the release of GA from FPVAG nanocomposite and ^aestimated using pseudo-second-order kinetics.