Clinical Study

Neoadjuvant Chemotherapy with FOLFOX4 Regimen to Treat Advanced Gastric Cancer Improves Survival without Increasing Adverse Events: A Retrospective Cohort Study from a Chinese Center

Table 3

Surgical and pathological results.

Items Neoadjuvant group
( )
Adjuvant group
( )
value*

Margins: (%)
 R019 (82.6)28 (80.0)0.807
 R1/24 (17.4)7 (20.0)
Postoperative complication: (%)
 Anastomotic leak1 (4.3)0 (0)0.507
 Respiratory infection2 (8.7)3 (8.6)
 Postoperative hemorrhage1 (4.3)1 (2.9)
 Postoperative bowel obstruction0 (0)2 (5.7)
Pathological staging
 T-stage: (%)
  T11 (4.3)2 (5.7)0.335
  T25 (21.7)2 (5.7)
  T34 (21.7)8 (22.9)
  T413 (52.1)23 (65.7)
 N-stage: (%)
  N08 (34.8)2 (5.7)0.034
  N13 (13.0)9 (25.7)
  N24 (17.4)10 (28.6)
  N38 (34.8)14 (40.0)
Number of nodes harvested: 16 (0–49)13 (3–40)0.886
Number of metastatic lymph nodes: 3 (0–14)6 (0–27)0.040

Comparisons for categorical variables performed using chi-square test. values for number of nodes harvested and metastatic lymph nodes were calculated by Wilcoxon test.