Gastroretentive Pulsatile Release Tablets of Lercanidipine HCl: Development, Statistical Optimization, and In Vitro and In Vivo Evaluation

Table 3

Floating lag time and total floating time of floating pulsatile release formulations.

Batch number	Formulation		FLT (sec)	TFT (h)
FP 1	PEO 20%	300 mg	64	8
FP 2		400 mg	130	10
FP 3		500 mg	140	>11
FP 14		480 mg	132	11
FP 4	PEO 30%	300 mg	68	9
FP 5		400 mg	164	11
FP 6		500 mg	181	>12
FP 7		400 mg	160	11
FP 8		400 mg	166	11
FP 9		400 mg	163	11
FP 10		400 mg	164	11
FP 11	PEO 40%	300 mg	70	>10
FP 12		400 mg	130	>11
FP 13		500 mg	220	>12
FP 14	PEO 20%	480.77 mg	137	>11

FLT: floating lag time; TFT: total floating time.