Research Article

Gastroretentive Pulsatile Release Tablets of Lercanidipine HCl: Development, Statistical Optimization, and In Vitro and In Vivo Evaluation

Table 6

Comparison of predicted and observed responses for the statistically optimized formulation FP 14.

FormulationResponseObservedPredictedRelative error (%)

FP 14Drug release lag time (, h)5.56.008.3
% drug release at 7 h ()77.0775.711.71
% drug release at 12 h ()98.95101.812.80