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The Scientific World Journal
Volume 2014, Article ID 439461, 5 pages
Research Article

Cytotoxicity of Doxycycline Effluent Generated by the Fenton Process

1Department of Biochemical and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, University of São Paulo, Bloco 16, Avenida Prof. Lineu Prestes 580, 05508-900 São Paulo, SP, Brazil
2Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, University Town Zeferino Vaz, Rua Monteiro Lobato 255, 13083-862 Campinas, SP, Brazil
3Department of Civil, Chemical and Environmental Engineering, Pole of Chemical Engineering, Genoa University, Via Opera Pia 15, 16145 Genoa, Italy

Received 30 July 2014; Accepted 3 September 2014; Published 14 October 2014

Academic Editor: Ricardo P. de Souza Oliveira

Copyright © 2014 Alexandre Augusto Borghi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This study aims at determining the Minimum Inhibitory Concentration with Escherichia coli ATCC 25922 and cytotoxicity to L929 cells (ATCC CCL-1) of the waste generated by doxycycline degradation by the Fenton process. This process has shown promise in this treatment thanks mainly to the fact that the waste did not show any relevant inhibitory effect on the test organism and no cytotoxicity to L-929 cells, thus demonstrating that the antibiotic properties were inactivated.