Functional Characterization of Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) N- and C-Terminal Domains during Xenopus laevis Development

Figure 1

Evolutionary conservation of TIMP-1 N- and C-terminal domains. Sequence analysis comparing amino acid sequence identity of X. laevis TIMP-1 N- and C-terminal domains versus known (at the time of publication) vertebrate species. Light purple boxes represent species whose N-terminal domains were more highly conserved with X. laevis TIMP-1 than their C-terminal domains. Light pink boxes represent species whose C-terminal domains were more highly conserved with X. laevis TIMP-1 than their N-terminal domains. Blue boxes represent species with equal conservation with both X. laevis TIMP-1 N- and C-terminal domains.