Research Article

Evaluation and Prediction of the HIV-1 Central Polypurine Tract Influence on Foamy Viral Vectors to Transduce Dividing and Growth-Arrested Cells

Figure 7

Dynamic function: logistic dose-response curve to predict and model viral infection cycle of retroviral replication efficiency in the A549 cells. The pMD9-based plasmids were tested to efficiently transduce dividing and growth-arrested cells (G1/S phase of cell cycle). Three conditions were analysed in the experiment: control (a); DMSO (b); aphidicolin (c).
487969.fig.007a
(a)
487969.fig.007b
(b)
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(c)