Median Preoptic Nucleus Mediates the Cardiovascular Recovery Induced by Hypertonic Saline in Hemorrhagic Shock

Figure 4

Effects of pharmacological blockade of the MnPO on changes in hematocrit level (a), plasma sodium concentration (b), and osmolarity (c) induced by hypertonic saline infusion in rats submitted to hemorrhage. Control group received nanoinjections of 150 mM NaCl () and experimental group received nanoinjections of 4 mM Muscimol () groups. Different from baseline, . The shaded area indicates the period of hemorrhage. Dashed line represents the moment of nanoinjection into the MnPO (muscimol or vehicle) and the black block indicates intravenous hypertonic saline infusion.

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