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The Scientific World Journal
Volume 2014, Article ID 496705, 10 pages
http://dx.doi.org/10.1155/2014/496705
Research Article

Inhibitory Effect of Cinobufagin on L-Type C Currents, Contractility, and C Homeostasis of Isolated Adult Rat Ventricular Myocytes

1Hebei Medical University, 361 East Zhongshan Road, Shijiazhuang, Hebei 050017, China
2The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050011, China
3Department of Pharmacology, Hebei University of Chinese Medicine, Shijiazhuang, Hebei 050200, China

Received 1 March 2014; Revised 15 April 2014; Accepted 23 April 2014; Published 25 May 2014

Academic Editor: Yunzeng Zou

Copyright © 2014 Pinya Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [5 citations]

The following is the list of published articles that have cited the current article.

  • Juanjuan Ma, Yonggang Gao, Ying Zhang, Fenghua Zhang, Zhenyi Liu, Shengjiang Guan, Li Chu, Xi Chu, Xuan Zhang, and Jianping Zhang, “Effects of total flavones from acanthopanax senticosus on l-type calcium channels, calcium transient and contractility in rat ventricular myocytes,” Phytotherapy Research, vol. 29, no. 4, pp. 533–539, 2015. View at Publisher · View at Google Scholar
  • Qiongtao Song, Li Chu, Xuan Zhang, Ying Zhang, Xue Han, Yuchong Xue, Tao Song, Xi Chu, Yuanyuan Zhang, and Jianping Zhang, “Effects of salvianolic acid B on L-type calcium channels and myocardial contractility in isolated rat ventricular myocytes and hERG K+ channels expressed in HEK293 cells,” Naunyn-Schmiedeberg's Archives of Pharmacology, vol. 390, no. 8, pp. 791–799, 2017. View at Publisher · View at Google Scholar
  • Guangping Liang, Tseyu Chung, Jinhua Guo, Rongrong Zhang, Wei Xü, Jason T. C. Tzen, and Renwang Jiang, “Novel cinobufagin oxime ether derivatives as potential Na+/K+-ATPase inhibitors: Synthesis, biological screening and molecular docking,” Chemical Research in Chinese Universities, vol. 33, no. 3, pp. 378–383, 2017. View at Publisher · View at Google Scholar
  • Tao Song, Xi Chu, Xuan Zhang, Qiongtao Song, Ying Zhang, Yuanyuan Zhang, Xue Han, Jianping Zhang, and Li Chu, “Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, inhibits L-type Ca2+ channels and contractility in rat ventricular myocytes,” Fundamental and Clinical Pharmacology, vol. 31, no. 3, pp. 340–346, 2017. View at Publisher · View at Google Scholar
  • Jing-Yi Zhang, Bin Zhang, Min Wang, Gui-Bo Sun, Wei Wang, Ping Liao, and Xiao-Bo Sun, “Calcium homeostasis and endoplasmic reticulum stress are involved in Salvianolic acid B-offered protection against cardiac toxicity of arsenic trioxide,” Oncotarget, vol. 8, no. 57, pp. 97384–97393, 2017. View at Publisher · View at Google Scholar