Research Article

Evaluation on Genotoxicity and Teratogenicity of Aqueous Extract from Cyclocarya paliurus Leaves

Table 2

The results of Ames test on C. paliurus leaf aqueous extract (for the second time). Data are expressed as mean ± SD.

Dose ( g/plate)TA97TA98TA100TA102
+S9 −S9+S9 −S9+S9 −S9+S9 − S9

5000
1000
200
40
8
Spontaneous reverse
Solvent controls
Positive controls

All the above data were average value of three plates standard deviation.
Positive controls: TA97 + S9, TA98 + S9, and TA100 + S9 adopted 2-AF (dose: 10.0  g/plate); TA97 − S9 and TA98 − S9 adopted 9-fluorenone (dose: 0.2 μg/plate); TA100 − S9 adopted NaN3 (dose: 1.5 μg/plate); TA102 + S9 adopted 1,8-mitoxanone (dose: 50.0 μg/plate); TA102 − S9 adopted MMC (dose: 0.5 μg/plate).