Optimization of Large-Scale Culture Conditions for the Production of Cordycepin with Cordyceps militaris by Liquid Static Culture

Table 10

Cordycepin production in the medium by liquid culture in different studies.

No.	Methodology	Working volume of the medium; v/v (mL/mL)	Cordycepin production (mg/L)	Total content of cordycepin in one bottle (mg)	References
1	Submerged culture	50/250	245.7	12.5	Mao et al., [32]
2	Submerged culture	50/250	420.5	21.03	Mao and Zhong [21]
3	Surface liquid culture	100/500	640	64	Masuda et al., [25]
4	Shaking + Static	100/250	2214.5	221.45	Shih et al., [34]
5	Surface liquid culture	100/500	2500	250	Masuda et al., [26]
6	Surface liquid culture	100/500	3100	310	Das et al., [30]
7	Surface liquid culture	100/500	8570	857	Das et al., [27]
8	Submerged culture	100/500	1644.21	164.42	Wen et al., [23]
9	Dark + Shaking	100/500	1015	101.5	Kang et al., [24]
10	Surface liquid culture	150/500	14300	2145	Masuda et al., [29]
11	Static liquid culture	700/1000	2008.48	1405.94	In this study