Optimization of Large-Scale Culture Conditions for the Production of Cordycepin with Cordyceps militaris by Liquid Static Culture

Table 9

ANOVA for response surface quadratic polynomial model for amino acid, nucleoside analogue, and time.

Source	Sum of quares	df	Mean Square	𝐹-value	𝑃-value Prob > 𝐹
Model	2.899𝐸+006	9	3.221𝐸+005	11.91	0.0003**
𝐴-𝐴	1378.39	1	1378.39	0.051	0.8260
𝐵-𝐵	1564.06	1	1564.06	0.058	0.8148
𝐶-𝐶	3.115𝐸+005	1	3.115𝐸+005	11.51	0.0068*
𝐴𝐵	63.06	1	63.06	2.331𝐸−003	0.9624
𝐴𝐶	2.702𝐸+005	1	2.702𝐸+005	9.99	0.0102*
𝐵𝐶	5468.49	1	5468.49	0.20	0.6626
𝐴^2	3.076𝐸+005	1	3.076𝐸+005	11.37	0.0071**
𝐵^2	3.073𝐸+005	1	3.073𝐸+005	11.36	0.0071**
𝐶^2	1.990𝐸+006	1	1.990𝐸+006	73.58	<0.0001**
Residual	2.705𝐸+005	10	27053.63
Lack of Fit	1.928𝐸+005	5	38561.98	2.48	0.1707
Pure Error	77726.41	5	15545.28
Cor Total	3.169𝐸+006	19

𝑅² = 0.9146; CV = 10.70%; Pred-𝑅² = 0.4162; Adj-𝑅² = 0.8378; Adeq Precision = 11.222; *5% significance level; **1% significance level.