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The Scientific World Journal
Volume 2014, Article ID 513160, 6 pages
Review Article

Multiple Sclerosis and Pregnancy: Current Considerations

1Head of Neurology, “Carol Davila” University of Medicine and Pharmacy, Colentina Clinical Hospital, No. 19-21 Stefan cel Mare Avenue, 020125 Bucharest, Romania
2Department of Neurology, Colentina Clinical Hospital, No. 19-21 Stefan cel Mare Avenue, 020125 Bucharest, Romania

Received 29 November 2013; Accepted 24 December 2013; Published 7 April 2014

Academic Editors: V. M. Rivera and E. J. Thompson

Copyright © 2014 Ioan Buraga and Roxana-Elena Popovici. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Multiple sclerosis is the most common neurological disease of young adults that causes major disability. In Romania, it is estimated that this disease has a prevalence of 35–40 per 100,000 inhabitants. It is a disease that begins at the age of 20–40 years and is 2-3 times more common in women than in men. More than half of patients with MS develop the disease in their fertile period of life; therefore, MS patients use contraceptive methods while being under our treatment. Since several therapeutic options have been implemented with good efficiency in the disease stabilization, increasingly more patients begin to wonder about the possibility of having a child and about the possible risks of pregnancy. The evolution during pregnancy and the lactation period has been favorable, with lower relapses and side effects comparable to those in the general population. In addition, babies born to mothers with MS have not had a significantly different mean gestational age or birth weight compared to babies born to healthy mothers.