Development and Optimization of Polymeric Self-Emulsifying Nanocapsules for Localized Drug Delivery: Design of Experiment Approach

Figure 12

Roentgenography study in guinea pigs. (a) Plain CUR. (b) CUR loaded optimized formulation (PSN) (P5) (where I: blank, II: after 30 min administration of formulation, III: after 1 h administration of formulation, IV: after 2 h administration of formulation, V: after 4 h administration of formulation, VI: after 6 h administration of formulation, VII: after 12 h administration of formulation, and VII: after 24 h administration of formulation).

(a)

(b)