Association of Helicobacter pylori Infection with Coronary Artery Disease: Is Helicobacter pylori a Risk Factor?

Table 2

Laboratory markers in groups of CAD.

	All patients; (𝑁=120)	CAD pos.		CAD neg.
		MVD; (𝑁=36)	SVD; (𝑁=26)	Insignificant; atherosclerosis; (𝑁=38)	Control group; (𝑁=20)
Laboratory markers
HP Seropositive (%)†§	62.5	76.3^#¥	70^#	52.8	50
CRP†	6.25 (4.55–7.95)	6.2 (2–10.2)	8.4* (3.8–13.1)	5.2 (3.7–6.7)	5.5 (2.4–8.6)
ESR†§	13.7 (11.1–16.3)	17.2* (10.8–23.5)	17* (10.7–23.3)	10.3 (7.1–13.5)	9.5 (5.2–13.8)
Total Chol	145 (138–152)	155.5 (142.5–168.5)	136.5 (122.3–150.7)	144.2 (132.6–155.8)	138.8 (120–157.8)
HDL††	48.5 (46.6–50.4)	49.5 (45.9–52.9)	43.8 (39.1–48.5)^##	53.6 (50.5–56.7)**	43.2 (39.9–46.5)
TG	149.7 (133.3–166.1)	154.6 (123–186.2)	150.7 (120.9–180.3)	140.9 (111.3–170.5)	156 (104.5–208.1)
LDL	69.6 (63.1–76.1)	79.3 (66.1–92.5)	61.8 (49.7–73.9)	68.6 (55.2–82)	64 (52–76)
Creatinine†	1.08 (0.95–1.2)	1.06 (0.99–1.2)	0.94 (0.89–1)*	0.95 (0.9–1)*	1.5 (0.76–2.2)

Categorical variables are presented in %, continuous variables as mean (95% confidence interval), and due to not normal distribution logarithmic transformation of the data was needed.^†significant difference among groups: ANOVA/Chi-square test (𝑃<0.050), ^††significant difference among groups: ANOVA/Chi-square test (𝑃<0.001), §significant difference between CAD pos. and CAD neg.: Chi-square test (𝑃<0.050), ^#significant difference versus insignificant atherosclerosis: Chi-square test (𝑃<0.050), ^##significant difference versus insignificant atherosclerosis: Bonferroni test (𝑃<0.001), *significant difference versus control group: Bonferroni test (𝑃<0.05), **significant difference versus control group: Bonferroni test (𝑃<0.001), and ¥significant difference versus control group: Chi-square test (𝑃<0.050).