Lens Extrusion from Laminin Alpha 1 Mutant Zebrafish
Figure 1
Laminin levels are downregulated in lama1 a69/a69 mutants. Immunofluorescent confocal microscopy showing laminin protein expression at 24-hpf. Eye from a wild type zebra fish embryo (a, b) showing normal distribution of laminin in the lens capsule at this stage. Eye from a lama1 a69/a69 mutant embryo showing downregulation of laminin expression (b, d). Laminin: red: DNA/Draq5: blue. lc: lens capsule. Scale bar = 35 m.
