Lens Extrusion from Laminin Alpha 1 Mutant Zebrafish
Figure 3
Lens fibers extrude from the eye in lama1 a69/a69 mutant zebrafish. (a, b) immunofluorescent confocal microscopy of aquaporin 0 in zebrafish wild type and lenses at 60 hpf shows that the expression of this lens fiber cell marker confined to the lens (a, b). In contrast, aquaporin 0 expression is detected both in the malformed lens and in material extruding out of the eye anteriorly in the mutants (c, d). Red: aquaporin 0; blue: Draq5. f: lens fiber cells; ce: corneal epithelium. Scale bar = 35 m.
