Formulation and Evaluation of Guggul Lipid Nanovesicles for Transdermal Delivery of Aceclofenac

Table 5

Pharmacokinetic parameters of selected nanovesicle gel formulations (PCG-1 and GLG-1) with respect to CF.

Formulation code	𝐶max (μg/mL)	𝑇max (hrs)	AUC (μg⋅hr/mL)
CF*	1.2±0.023	4	11.6
PCG-1	4.98±0.95	4	83.9
GLG-1^†	7.32±0.29	8	141.2

∗1 g formulation equivalent to 15 mg Aceclofenac.
^†500 mg formulation equivalent to 5 mg of Aceclofenac.
All data expressed as mean ± S.D.; 𝑛=6; (𝑃≤0.05).