Review Article
Extracorporeal Ultrasound-Guided High Intensity Focused Ultrasound: Implications from the Present Clinical Trials
Table 1
List of the therapeutic strategies applied during HIFU for cancers.
| | Disease and treatment | Regimen |
| | Liver | | | TACE | ADM | | BLM | | DDP | | 5-FU + ADM | | 5-FU + DDP | | 5-FU + EPI | | 5-FU + GEM | | GEM + Oxa | | 5-FU + ADM + CBP | | 5-FU + ADM + MMC | | 5-FU + CBP + MMC | | 5-FU + DDP + EPI | | 5-FU + DDP + MMC | | 5-FU + EPI + Oxa | | ADM + FUDR + MMC | | FUDR + Oxa + THP | | 5-FU + (ADM/THP) + (DDP/Oxa) | | 5-FU + AMD + DDP + MMC | | 5-FU + DDP + EPI + MMC | | 5-FU + MMC + THP + CF | | 5-FU, (DDP/Oxa), EPI, GEM | | 5-FU, DDP, EPI, HCPT, MMC | | Chemotherapy | Capecitabine | | 5-FU + CBP | | DDP + GEM | | 5-FU + ADR + DDP | | 5-FU + CTX + VCR | | ADR + CTX + DDP | | 5-FU + Oxa + CF | | Radiotherapy | 3DCRT | | Stereotactic | | Biotherapy | Thymosin α1 | | Tumor necrosis factor | | DCCIK | | Surgery | | | Ethanol | | | Others | Chlorin e6 | | Thalidomide |
| | Pancreas | | | Chemotherapy | 5-FU | | Capecitabine | | DDP | | GEM | | 5-FU + CF | | 5-FU + GEM | | GEM + Capecitabine | | GEM + DDP | | GEM + Oxa | | 5-FU + GEM + CF | | Arterial infusion | GEM | | 5-FU + GEM | | 5-FU + DDP + EPI | | 5-FU + GEM + Oxa | | DDP + GEM + Interferon | | 5-FU + EPI + MMC + CF | | Radiotherapy | 3DCRT | | Celiac ganglia destruction | | | Biotherapy | Mycobacterium phlei F.U.36 | | Octreotide |
| | Ovary | | | Chemotherapy | BLM + DDP + VCR | | CTX + DDP + VCR | | Radiotherapy | |
| | Uterine cervix | | | Chemotherapy | 5-FU + DDP + CF | | CTX + BLM + DDP | | 5-FU + DDP + PTX + CF | | Radiotherapy | |
| | Vagina | | | Radiotherapy | |
| | Bone | | | Arterial infusion | DDP | | ADM, DDP, MTX, IFO | | Chemotherapy | ADM + DDP | | HDMTX + VCR | | ADM + MTX + IFO | | ADM, DDP, MTX, IFO | | Radiotherapy | |
| | Breast | | | Chemotherapy | PTX + ADM | | PTX + EPI | | 5-FU + ADM + CTX | | 5-FU + CTX + EPI | | 5-FU + CTX + MTX | | CTX + EPI + Tegafur | | Hormone therapy | Tamoxifen | | Radiotherapy | | | Endoscopic axillary node dissection | |
| | Soft tissues | | | Chemotherapy | ADM + DDP | | DDP + IFO | | CBP + VP-16 | | ADM + DTIC + IFO | | CBP + EPI + VCR | | Arterial infusion | DDP | | ADM + DTIC + IFO | | Radiotherapy | | | Surgery | |
| | Retroperitoneal lesions | | | Radiotherapy | 3DCRT | | Chemotherapy | N/A | | Surgery | |
| | Esophagus | | | Chemotherapy | DDP + PTX | | 5-FU + DDP + CF |
| | Stomach | | | Chemotherapy | 5-FU + DDP + PTX | | 5-FU + Oxa + CF |
| | Colorectum | | | Chemotherapy | 5-FU + ADM + MTX | | 5-FU + Oxa + CF | | Radiotherapy | |
| | Kidney | | | Biotherapy | Interferon |
| | Prostate | | | Hormone therapy | Orchidectomy | | Flutamide/bicalutamide | | Leuprorelin/goserelin | | Radiotherapy |
125I | | External beam | | Transurethral resection | |
| | Bladder | | | Infusion | ADM | | HCPT | | MMC | | Radiotherapy | |
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5-FU: 5-fluorouracil; ADM: adriamycin; BLM: bleomycin; CBP: carboplatin; CF: calcium folinate; CTX: cyclophosphamide; DDP: cisplatin; DTIC: dacarbazine; EPI: epirubicin; FUDR: floxuridine; GEM: gemcitabine; HCPT: hydroxycamptothecin; IFO: ifosfamide; MMC: mitomycin C; MTX: methotrexate; Oxa: oxaliplatin; PTX: paclitaxel; THP: pirarubicin, VCR: vincristine; VP-16: etoposide.
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