Table 1: Characteristics of studies included in the meta-analysis.

StudyYearCountryEthnicityCancer typeSource of
controls
Genotype
methods
Genotype (case/control)HWE
TotalWT HoHtVR Ho( value)

HSP70-2AAAGGG

Chouchane et al. [11]1997aTunisiaAfricanNon-Hodgkin’s lymphomaPBAFLP44/1064/2228/8212/20
Chouchane et al. [11]1997bTunisiaAfricanBreastPBAFLP40/1064/2226/8210/20
Ferrer-Ferrer et al. [12]2013Costa RicaMixedGastricHBRFLP39/797/3026/326/170.137
Jalbout et al. [14]2003TunisiaAfricanNasopharyngealPBAFLP140/27440/10168/13832/350.251
Jeng et al. [15]2008Taiwan (China)AsianHepatocellularHBAFLP150/15028/7055/6567/150.987
Kádár et al. [16]2008HungaryEuropeanMultiple myelomaPBPCR-RFLP94/14134/6560/76*NA
Li et al. [17]2010ChinaAsianHepatocellularHBPCR145/12748/5671/6226/90.139
Medhi et al. [18]2013IndiaAsianHepatocellularPBPCR-RFLP185/200111/15659/4015/40.453
Mestiri et al. [19]2001TunisiaAfricanBreastPBPCR243/17452/35123/13068/90
Rehman et al. [20]2009IndiaAisianKangri cancerPBPCR-RFLP118/9510/24103/705/10
Shibata et al. [23]2009JapanAsianGastricHBPCR-RFLP225/20046/33173/1556/120
Srivastava et al. [24]2012IndiaAsianPancreaticPBPCR-RFLP50/5013/3329/158/20.858
Tóth et al. [25]2007HungaryEuropeanColorectalPBPCR-RFLP183/14169/6587/5727/190.258
Ucisik-Akkaya et al. [26]2010aUKEuropeanChildhood ALLPBPCR-RFLP114/41458/13947/1999/760.747
Ucisik-Akkaya et al. [26]2010bMexicoMixedChildhood ALLPBPCR-RFLP92/23527/6151/11114/630.397
Wang et al. [27]2010ChinaAsianLungHBPCR-RFLP159/20257/5672/10030/460.915
Zagouri et al. [28]2012GreeceEuropeanBreastHBPCR113/12424/3282/767/160.006

HSP70-homTTTCCC

Chouchane et al. [11]1997aTunisiaAfricanNon-Hodgkin’s lymphomaPBAFLP44/10631/9810/83/00.686
Chouchane et al. [11]1997bTunisiaAfricanBreastPBAFLP40/10631/988/81/00.686
Ferrer-Ferrer et al. [12]2013Costa RicaMixedGastricHBRFLP39/7934/555/230/10.409
Guo et al. [13]2011ChinaAsianLungPBTaqMan1152/1152674/695412/41166/460.124
Medhi et al. [18]2013IndiaAsianHepatocellularPBPCR-RFLP185/200178/1447/420/140.0001
Rehman et al. [20]2009IndiaAisianKangri cancerPBPCR-RFLP118/9560/2856/602/70.001
Sfar et al. [22]2010TunisiaAfricanProstatePBPCR-RFLP101/10577/6520/324/80.164
Ucisik-Akkaya et al. [26]2010aUKEuropeanChildhood ALLPBTaqMan105/37167/24630/1038/220.015
Ucisik-Akkaya et al. [26]2010bMexicoMixedChildhood ALLPBTaqMan99/24587/21411/271/40.008
Wang et al. [27]2010ChinaAsianLungHBPCR-RFLP159/20295/14156/598/20.120

HSP70-1GGGCCC

Guo et al. [13]2011ChinaAsianLungPBTaqMan1152/1152589/564457/486106/1020.853
Partida-Rodríguez et al. [21]2010MexicoMixedGastricHBPCR-RFLP42/1064/5937/411/60.746
Ucisik-Akkaya et al. [26]2010aUKEuropeanChildhood ALLPBTaqMan106/36547/13745/16214/660.139
Ucisik-Akkaya et al. [26]2010bMexicoMixedChildhood ALLPBTaqMan99/25062/12732/985/250.347
Wang et al. [27]2010ChinaAsianLungHBPCR-RFLP159/20257/10465/8237/160.977

HWE, Hardy-Weinberg equilibrium; was calculated by goodness-of fit -test, was considered statistically significant; NA, not available. Ht, heterozygote; VR Ho, variant homozygote; WT Ho, wide-type homozygote; *Numbers of Ht + VR Ho.