A Schiff Base-Derived Copper (II) Complex Is a Potent Inducer of Apoptosis in Colon Cancer Cells by Activating the Intrinsic Pathway
Figure 3
(a) Untreated HT-29 cells after 72 h demonstrated normal structure without prominent apoptosis or necrosis. Early apoptosis features, including blebbing and chromatin condensation, were observed after (b) 24 and (c) 48 h of treatment with Cu(BrHAP)2. (d) Late apoptosis was noticed after 72 h of Cu(BrHAP)2 treatment (magnification: 200x). VI: viable cells; BL: blebbing of the cell membrane; CC: chromatin condensation; LA: late apoptosis.
