Research Article

A Schiff Base-Derived Copper (II) Complex Is a Potent Inducer of Apoptosis in Colon Cancer Cells by Activating the Intrinsic Pathway

Table 1

Inhibitory effects of Cu(BrHAP)2 on the proliferation of human normal and cancer cells. Cells were treated with various concentrations of Cu(BrHAP)2 for 24, 48, and 72 h. The IC50 values were analyzed by nonlinear regression analysis.

Cell line ClassificationIC50 ( g/mL)
24 h48 h72 h

HT-29Colon
cancer cells
CCD 841 Normal
colon cells
50<50<50<