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Glossary | Central SAN model | Peripheral SAN model |
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| Cell membrane capacitance | 20 pF | 65 pF |
| Maximum conductance | 0 μS/pF | |
| Maximum conductance | μS/pF | |
| Maximum conductance | μS/pF | |
| Maximum conductance | μS/pF | |
| Maximum conductance | μS/pF | |
| Maximum conductance | μS/pF | |
| Maximum conductance | μS/pF | |
| Maximum conductance | μS/pF | 0 μS/pF |
| Apparent reversal potential for | 46.4 mV | 46.4 mV |
| Apparent reversal potential for | 37.4 mV | 37.4 mV |
| Extracellular Na+ concentration | 140 mM | 140 mM |
| Extracellular K+ concentration | 5.4 mM | 5.4 mM |
| [Ach] that produces a half-maximal activation of | 0.28 μM | 0.28 μM |
| [Ach] that produces a half-maximal block of | 0.09 μM | 0.09 μM |
| [Iso] that produces a half-maximal increase of | 7 nM | 7 nM |
| [Ach] that produces a half-maximal shift of activation curve | μM | μM |
| [Iso] that produces a half-maximal shift of activation curve | 13.5 nM | 13.5 nM |
| [Iso] that produces a half-maximal increase of | 19 nM | 19 nM |
| [Iso] that produces a half-maximal shift of activation curve | 7.5 nM | 7.5 nM |
| [Iso] that produces a half-maximal decrease of | 24 nM | 24 nM |
| [Iso] that produces a half-maximal Increase of | 33 nM | 33 nM |
| Rate constant of Ca2+ uptake by of the network SR | 0.01 mM/ms | 0.02 mM/ms |
| affected by [Ach] and Hill coefficient | 1.5 | 1.5 |
| affected by [Ach] and Hill coefficient | 0.69 | 0.69 |
| SR Ca2+ uptake and Hill coefficient | 2 | 2 |
| affected by [Iso] and Hill coefficient | 0.392 | 0.392 |
| Percentage change of conductance induced by DelF1617 mutation | 0.38 | 0.38 |
| Percentage change of the fast-inactivation time constants of induced by DelF1617 mutation | 2.18 | 2.18 |
| Percentage change of the slow-inactivation time constants of induced by DelF1617 mutation | 2.75 | 2.75 |
| Parameter of the shift in the inactivation curve of induced by DelF1617 mutation | 0.128 | 0.128 |
| Maximum fraction of block caused by Ach | 0.56 | 0.56 |
| Maximum shift of activation curve caused by Ach | −7.2 mV | −7.2 mV |
| Maximum percentage increase of caused by Iso | 0.54 | 0.54 |
| Maximum percentage increase of caused by Iso | 1.87 | 1.87 |
| Maximum percentage increase of caused by Iso | 1.0 | 1.0 |
| Maximum activation curve shift of caused by Iso | 9.62 mV | 9.62 mV |
| Maximum activation curve shift of caused by Iso | −15 mV | −15 mV |
| Maximum decrease of caused by Iso | 3.0 | |
| Percentage increase of the SR Ca2+ release fluxes caused by Iso | 0.2 | |
| Percentage decrease of the SR Ca2+ uptake caused by Iso | 0.2 | |
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