Significance of Normalization on Anatomical MRI Measures in Predicting Alzheimer’s Disease

Table 7

Univariate analysis of surface area for left and right hemispheres*.

Surface area; normalization	Left hemisphere			Right hemisphere
	Raw	ICV	Total area	Raw	ICV	Total area
Bankssts	<0.01	<0.05	<0.001	ns	ns	ns
Frontalpole	<0.01	<0.05	<0.05	ns	ns	ns
Paracentral	<0.05	<0.01	<0.01	ns	ns	ns
Transverse-temporal	ns	<0.01	<0.01	ns	ns	ns
Lingual	ns	ns	<0.01	ns	ns	ns
Postcentral	ns	<0.01	<0.01	ns	ns	ns
Insula	ns	<0.05	<0.01	ns	ns	ns
Cuneus	ns	ns	<0.05	ns	ns	<0.05
Temporalpole	ns	ns	ns	<0.01	<0.01	<0.001
Superior-frontal	ns	<0.05	<0.01	ns	<0.05	<0.01
Precentral	ns	ns	<0.05	ns	<0.05	<0.01
Fusiform	ns	ns	<0.05	ns	ns	<0.01
Inferiortemporal	ns	ns	ns	ns	ns	<0.01
Inferiorparietal	ns	ns	ns	ns	ns	<0.05

∗Two-way Student’s 𝑡-test is used for univariate analysis with a significant level of 0.05 for 𝑃 value.