Research Article

Assessment of Serum Acylated Ghrelin in Children and Adolescents with Chronic Liver Diseases: Relation to Nutritional Status

Table 1

Clinical and laboratory data among cases and controls.

Cases ()Controls ()

Age (years)7.55 ± 3.46 (1–16)7.6 ± 2.50 (1–15.5)1.240.22
Height SDS−1.75 ± 1.58 (−3.82–0.95)+0.69 ± 1.7 (0.99–1.84)5.710.03*
BMI (Kg/m2)14.2 ± 1.06 (12.5–18.71)20.2 ± 0.91 (14.1–23.9)8.890.0001***
BMI SDS−1.85 ± 0.21 (−3.15–0.98)+0.89 ± 0.28 (0–1.54)6.110.0001***
TSFT percentile 16 ± 5.5 (4.15–55.70)66 ± 6.5 (25.15–78.70)21.800.0001***
SSFT percentile18 ± 5.5 (6.15–57.70)65 ± 4.4 (23–77.70)19.890.0001***
Haemoglobin (g/dL) 10.4 ± 1.19 (9–12.5)13 ± 1.33 (10.5–14.5)7.110.01*
ALT (IU/L)39.6 ± 13.35 (18–98)15.65 ± 3.35 (19.5–34.0)7.220.01*
AST (IU/L)36 ± 10.25 (19–70)12 ± 2.5 (5.12–32.5)6.550.01*
Total bilirubin (mg/dL) 1.94 ± 0.88 (0.5–5.89)0.5 ± 0.1 (0.2–1.0)5.660.03*
Albumin (g/dL) 3.05 ± 0.46 (1.89–4.2)4.88 ± 0.56 (3.82–5.92)4.890.04*
PT (seconds)14.42 ± 1.64 (12–18.7)11.5 ± 1.20 (10–12.45)5.100.03*
Ghrelin (pg/mL)130 ± 46.13 (40–210)38.4 ± 18.11 (12–62)15.980.0001***

Results are expressed as mean ± SD and range; and , SDS: standard deviation score, BMI: body mass index, TSFT: triceps skin fold thickness, SSFT: subscapular skin fold thickness, ALT: alanine aminotransferase, AST: aspartate aminotransferase, and PT: prothrombin time.