Assessment of Serum Acylated Ghrelin in Children and Adolescents with Chronic Liver Diseases: Relation to Nutritional Status
Table 2
Clinical and laboratory data according to severity of liver disease among studied cases ().
Child A ()
Child B ()
Child C ()
Age (years)
6.5 ± 4.5 (1–13.5)
5.2 ± 6.2 (0.5–15)
7.6 ± 3.0 (1–16)
0.19
0.75
Height SDS
−1.75 ± 1.6 (−2.06–0.95)
−2.28 ± 0.46 (−3.02–0.12)
−3.36 ± 0.51 (−3.82–0.33)
6.81
0.04*
BMI (Kg/m2)
16.10 ± 0.51 (15–18.71)
14.10 ± 0.51 (13.7–18)
13.19 ± 0.12 (12.5–17.5)
7.22
0.031*
BMI SDS
−1.12 ± 0.62 (−1.4–0.98)
−1.5 ± 0.66 (−2.43–0.34)
−2.1 ± 0.72 (−3.15–0.88)
6.89
0.030*
TSFT percentile
53 ± 1.5 (15–55.7)
25 ± 5.5 (18–50.5)
12 ± 4.5 (4.15–48)
8.77
0.02*
SSFT percentile
54 ± 4.4 (20–57.7)
28 ± 2.3 (20–50.4)
15 ± 4.7 (6.15–45)
6.88
0.021*
Haemoglobin (g/dL)
11.1 ± 1.19 (9.5–12.5)
12.3 ± 0.25 (10–12.5)
9.8 ± 0.99 (9–12.4)
5.56
0.04*
ALT (IU/L)
38 ± 12.35 (18–66)
55 ± 10.15 (20–85)
82 ± 11.30 (58–98)
9.33
0.030*
AST (IU/L)
29 ± 5.15 (19–54)
42 ± 10.05 (22–65)
58 ± 8.25 (28–70)
6.18
0.04*
Total bilirubin (mg/dL)
0.8 ± 0.28 (0.55–3.1)
1 ± 0.11 (0.5–3.8)
1.5 ± 0.08 (0.6–5.89)
5.91
0.04*
Albumin (g/dL)
3.30 ± 0.30 (2.9–4.2)
2.42 ± 0.17 (2.20–2.60)
2.01 ± 0.11 (1.89–2.99)
5.62
0.032*
PT (seconds)
12.5 ± 0.24 (12–14.80)
14 ± 1.62 (12.5–17.8)
16 ± 1.20 (12.5–18.7)
6.01
0.041*
Ghrelin (pg/mL)
99 ± 16.03 (40–125)
132 ± 19.23 (57–173)
189 ± 12.5 (60–210)
28.19
0.0001***
Results are expressed as mean ± SD and range; , and ; SDS: standard deviation score, BMI: body mass index, TSFT: triceps skin fold thickness, SSFT: subscapular skin fold thickness, ALT: alanine aminotransferase, AST: aspartate aminotransferase, and PT: prothrombin time.
