Assessment of Serum Acylated Ghrelin in Children and Adolescents with Chronic Liver Diseases: Relation to Nutritional Status
Table 3
Clinical and laboratory data among cases with normal versus elevated serum ghrelin.
Elevated ghrelin ()
Nonelevated ghrelin ()
Age (years)
7.50 ± 3.46 (1–16)
7.6 ± 1.50 (2–15.5)
0.24
0.52
Height SDS
−1.85 ± 1.58 (−3.11–0.95)
−1.70 ± 1.4 (−3.82–0.95)
0.71
0.31
BMI (Kg/m2)
13.2 ± 0.56 (12.5–15.71)
16.89 ± 0.20 (13.5–18.71)
7.89
0.001**
BMI SDS
−2.25 ± 0.31 (−3.15–0.88)
−1.05 ± 0.11 (−2.12–0.98)
5.91
0.01*
TSFT percentile
12 ± 4.5 (4.15–45.6)
36 ± 6.7 (22–55.70)
19.80
0.0001***
SSFT percentile
14 ± 3.5 (6.15–47.50)
40 ± 5.5 (15.8–57.70)
17.89
0.0001***
Haemoglobin (g/dL)
10 ± 0.99 (9–11.8)
11.8 ± 0.20 (9–12.5)
4.33
0.04*
ALT (IU/L)
52.6 ± 12.35 (22–98)
28 ± 10.05 (18–65)
6.12
0.02*
AST (IU/L)
54 ± 7.25 (28–70)
24 ± 5.15 (19–55)
8.55
0.01*
Total bilirubin (mg/dL)
3.04 ± 0.78 (0.9–5.89)
0.98 ± 0.24 (0.5–2.3)
6.66
0.02*
Albumin (g/dL)
2.05 ± 0.26 (1.89–4.0)
3.61 ± 0.16 (2.1–4.20)
4.23
0.041*
PT (seconds)
16.02 ± 1.34 (12.5–18.7)
13 ± 1.23 (12–17.6)
6.10
0.03*
Ghrelin (pg/mL)
170 ± 16.13 (72–210)
51 ± 10.12 (40–62.5)
18.91
0.0001***
Results are expressed as mean ± SD and range; , , and ; SDS: standard deviation score, BMI: body mass index, TSFT: triceps skin fold thickness, SSFT: subscapular skin fold thickness, ALT: alanine aminotransferase, AST: aspartate aminotransferase, and PT: prothrombin time.
