Significance of Algal Polymer in Designing Amphotericin B Nanoparticles

Figure 12

Renal toxicity of Fungizone, CS-AmB-NP, CS-POR-AmB-NP, CS-NP (blank), and CS-POR-NP (blank) nanoparticles. The concentrations of (a) BUN and (b) Creatinine in serum were determined at 1 mg/kg, 4 mg/kg, and 8 mg/kg dose intervals. From 8 mg/kg of Fungizone and CS-AmB NPs no survival of mice was observed. Values represent mean ± SD ().

(a)

(b)